However, there were no significant variations in bone mineral density in the lumbar spine or proximal femur among any from the cure groups. The authors pointed out the importance of thinking about the effect of vitamin D on bone health when comparing the results of vitamin K supplementation studies, particularly when both vitamin K and vitamin D (and/or calcium) are administered to the remedy team but not the placebo team [38]. The administration of vitamin D and/or calcium in conjunction with vitamin K could partly reveal why some scientific studies have discovered that vitamin K supplementation improves bone health and fitness while others haven't.
While vitamin K is involved with the carboxylation of osteocalcin, it is actually unclear whether or not supplementation with any method of vitamin K decreases the chance of osteoporosis. In 2006, Cockayne and colleagues done a scientific review and meta-Assessment of randomized managed trials that examined the results of vitamin K supplementation on bone mineral density and bone fracture [35]. Most of the trials ended up done in Japan and associated postmenopausal Women of all ages; demo duration ranged from six to 36 months.
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